Gorham’s Disease

Gorham disease is characterized by proliferation of the vasculature of the bone in the early stage, followed by gradual osteolysis and fibrous replacement

Image from Neurology.org (link)

A 46-year-old man had tenderness at the left occiput, without neurologic symptoms, for 5 years. Head CT and MRI  disclosed focal calvarial thinning without a soft tissue mass, and normal brain parenchyma.  A PET scan did not suggest malignancy. Histologic examination demonstrated dilated vascular channels and abundant fibrous tissue without osteoclasts or malignant cells

Wikipedia article (link)

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