Lisch Nodules

Lisch nodule is a pigmented hamartomatous nodular aggregate of dendritic melanocytes affecting the iris,  named after Austrian ophthalmologist Karl Lisch (1907–1999), who first recognized them in 1937.  These nodules are found in neurofibromatosis type 1, and are present in greater than 94% of patients over the age of six.   They are clear, yellow-brown, oval to round, dome-shaped papules that project from the surface of the iris.   Nodules typically do not affect vision, but are very useful in diagnosis. (Adapted from Wikipedia)


image of Lisch nodules

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