A neuromuscular junction (NMJ) is the synapse or junction of the axon terminal of a motor neuron with the motor end plate, the highly-excitable region of muscle fiber plasma membrane responsible for initiation of action potentials across the muscle’s surface, ultimately causing the muscle to contract. In vertebrates, the signal passes through the neuromuscular junction via theneurotransmitter acetylcholine. (wikipedia)
Image from Heidelberg University (link)
Histological visualization of neuromuscular junctions in muscle. The motor neuron is depicted in green (anti-neurofilament immunohistochemistry) and the acetylcholine receptor clusters on the muscle fiber membrane in red (using fluorescently labeled alpha-bungarotoxin).
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