In columnar epithelium, the cells are taller than they are wide. Goblet cells which look like balloons suspended in the epithelium secrete mucus; the clear “balloon” in the apical region of each goblet cell is where the stored mucus is located (mucus does not react with H&E stain). In the colon, villi are absent and, instead, a simple columnar epithelium forms the intestinal “glands,” which are invaginations made up of mostly goblet cells.
Virtual Microscopy (link). Univ of Michigan. This is colon histologyOther similar posts