Simple Columnar Epithelium – Colon

In columnar epithelium, the cells are taller than they are wide.   Goblet cells which look like balloons suspended in the epithelium secrete mucus; the clear “balloon” in the apical region of each goblet cell is where the stored mucus is located (mucus does not react with H&E stain). In the colon, villi are absent and, instead, a simple columnar epithelium forms the intestinal “glands,” which are invaginations made up of mostly goblet cells.

Virtual Microscopy (link). Univ of Michigan.  This is colon histology

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