Tag Archives: fibroblasts

Fibroblast – confocal

A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen,[1] the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals. (from wikipedia)

Image from foxtail_1 flickr (link).   Image by Kristi Decourcy, Ph.D, Virginia Tech.

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Fibroblasts

While the epidermis of mammalian skin contains primarily kerotinocytes, the dermis is composed largely of fibroblasts. The dermis is a type of connective tissue, and fibroblasts produce the two major structural components of its extracellular matrix: collagen fibers, which give the dermis strength and traction; and, elastin, which make the dermis stretchable and flexible. Unlike epithelial cells, fibroblasts do not form flat, monolayers but rather can migrate around the extracellular matrix. Thus, while epithelial cells line the body, fibroblasts are the ones to “sculpt it.” (by Tom Deerinck)Image from cell.com (link)  Image from Tom Deerinc, NCMIR and UCSD

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